{"id":49273,"date":"2020-01-02T16:04:23","date_gmt":"2020-01-02T16:04:23","guid":{"rendered":"https:\/\/merryjane.com\/scientists-just-discovered-a-more-potent-natural-form-of-thc\/"},"modified":"2020-01-02T16:04:23","modified_gmt":"2020-01-02T16:04:23","slug":"scientists-just-discovered-a-more-potent-natural-form-of-thc","status":"publish","type":"post","link":"https:\/\/merryjane.com\/news\/scientists-just-discovered-a-more-potent-natural-form-of-thc\/","title":{"rendered":"Scientists Just Discovered a More Potent, Natural Form of THC"},"content":{"rendered":"<p>A newly discovered <a href=\"https:\/\/merryjane.com\/culture\/wtf-are-cannabinoids-and-what-are-their-benefits\" target=\"_blank\" rel=\"noopener\"><u>cannabinoid<\/u><\/a> may completely change our understanding of cannabis. And the coolest part? It\u2019s a stronger version of weed\u2019s most famous compound: THC.<\/p>\n<p>Earlier this week, Italian researchers published their findings in the latest edition of <a href=\"https:\/\/www.nature.com\/articles\/s41598-019-56785-1.pdf\" rel=\"nofollow noopener\" target=\"_blank\"><u><em>Nature<\/em><\/u><\/a><em>. <\/em>After analyzing a medical marijuana strain grown exclusively by <a href=\"https:\/\/gulfnews.com\/world\/europe\/in-italy-the-army-provides-marijuana-and-thats-a-problem-1.2137630\" rel=\"nofollow noopener\" target=\"_blank\"><u>Italy\u2019s military<\/u><\/a>, dubbed FM2, the researchers found unusual chemical signatures, which eventually led to identifying and isolating the previously unknown cannabinoid, called tetrahydrocannabiphorol or THCP.&nbsp;<\/p>\n<p>THCP is nearly identical to THC \u2014 the chemical in cannabis that causes intoxication \u2014 with the exception of a couple extra carbon atoms on the molecule\u2019s tail end. Those extra carbon atoms are critical for affecting THCP\u2019s ability to bind to the body\u2019s <a href=\"https:\/\/merryjane.com\/health\/exploring-the-endocannabinoid-system\" target=\"_blank\" rel=\"noopener\"><u>CB1 and CB2 receptors<\/u><\/a>, the cell receptors that directly interact with weed compounds to help us heal or get us high.<\/p>\n<p>According to the study, THCP binds much stronger to the CB1 and CB2 receptors than THC does. In fact, THCP binds over 30 times stronger to the CB1 receptor \u2014 the receptor that triggers weed\u2019s high \u2014 than THC.&nbsp;<\/p>\n<p>When THCP was given to mice, the researchers found that just half the standard THC dose, or 5mg\/kg THCP, was enough to intoxicate the rodents. However, THCP has not yet been administered to human subjects, so whether it actually gets people more lit remains untested.&nbsp;<\/p>\n<p><iframe loading=\"lazy\" allowfullscreen=\"true\" frameborder=\"0\" width=\"640\" height=\"430\" scrolling=\"no\" src=\"https:\/\/merryjane.com\/embed\/gallery\/weed-porn-cannabis-up-close\/weed-porn-cannabis-up-close-1\" ><\/iframe><\/p>\n<p>So, what does this discovery mean for our understanding of cannabis and its medical applications?&nbsp;<\/p>\n<p>\u201c[It] is reasonable to suppose that other cannabis varieties may contain even higher percentages of \u03949-THCP,\u201d the researchers wrote in the study. \u201cIt is also important to point out that there exists an astonishing variability of subject response to a cannabis-based therapy even with an equal \u03949-THC dose.\u201d<\/p>\n<p>In other words, people may experience wildly different effects from weed because of other cannabinoids, terpenes, or <a href=\"https:\/\/merryjane.com\/news\/weeds-most-potent-pain-killing-compounds-may-not-be-thc-or-cbd\" target=\"_blank\" rel=\"noopener\"><u>flavonoids<\/u><\/a> that we still don\u2019t know about. After all, we\u2019ve likely been smoking\/eating\/vaping\/dabbing THCP for years without ever realizing it.&nbsp;<\/p>\n<p>What other powerful compounds are lurking inside of cannabis that science hasn\u2019t yet identified? And will these new discoveries completely upend our current understanding of cannabis science? Time will tell, and we\u2019ll continue to cover new updates as they reveal themselves.<\/p>\n<p><em>Follow Randy Robinson on <\/em><a href=\"https:\/\/twitter.com\/RanDieselJay\" rel=\"nofollow noopener\" target=\"_blank\"><u><em>Twitter<\/em><\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The compound, THCP, may be 30 times stronger than the THC we all know and love.<\/p>\n","protected":false},"author":2,"featured_media":49274,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3036],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Scientists Just Discovered a More Potent, Natural Form of THC - Merry Jane<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/merryjane.com\/news\/scientists-just-discovered-a-more-potent-natural-form-of-thc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists Just Discovered a More Potent, Natural Form of THC - 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